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Q: Which of the following choices, upon reaction with the molecule below, will NOT result in a carboxylic acid derivative? A SOCl2 B PBr3 C Cl2 D PCl3 Tags: Carboxylic Acids | Acid Derivatives |

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Q: Acetone (on the left) and acetyl chloride (on the right) are shown below. Regarding deprotonation of a hydrogen from the left methyl group (for both molecules), which molecule will have the lower pKa and why? A The molecule on the left will have the lower pKa and destabilize the conjugate base B The molecule on the left will have the lower pKa and stabilize the conjugate base C The molecule on the right will have the lower pKa and stabilize the conjugate base D The molecule on the right will have the lower pKa and destabilize the conjugate base Tags: Aldehydes and Ketones | Acid/Base Equilibria | Acid Derivatives |

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Q: The following molecule is an activated carboxylic acid derivative, which can be used as an acylating agent. Which of the following is TRUE regarding its nitrogen-based leaving group? A The nitrogen-based leaving group is a poor leaving group since there is more resonance stabilization in its current form. B The nitrogen-based leaving group is a poor leaving group since it is large and uncharged. C The nitrogen-based leaving group is a good leaving group since its negative charge (upon leaving) is stabilized by resonance. D The nitrogen-based leaving group is a good leaving group since it retains its neutral charge even after leaving the molecule. Tags: Molecular Structure | Acid Derivatives |

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Q: Gallic acid, as shown, is reacted with another carboxylic acid. If water is produced in the reaction, what type of molecule is formed in addition to the water? A acid anhydride B ketone C aldehyde D alcohol Tags: Carboxylic Acids | Acid Derivatives |

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Q: Methanesulfinic acid can be modified to which of the following molecules in order to increase its acidity? A B C D Tags: Acid Derivatives |

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Q: The structures of triflic acid and trichloroacetic acid are shown. How would the pKa of the two acids be compared? A The pKa of triflic acid would be higher because it is a stronger acid. B The pKa of triflic acid would be lower because it is a stronger acid. C The pKa of trichloroacetic acid would be higher because it is a stronger acid. D The pKa of trichloroacetic acid would be lower because it is a stronger acid. Tags: Acid Derivatives | Carboxylic Acids | Acid/Base Equilibria |

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Q: If all of the following molecules are present at equal concentrations in a neutral-pH aqueous solution, which would have the highest vapor pressure above the solution? A B C D Tags: Carboxylic Acids | Intermolecular Forces | Alcohols | Acid Derivatives |

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Q: What modification could be made to increase the volatility of a fatty acid? A Place it a high-pH solution. B Convert it to an ester. C Lengthen the hydrophobic tail. D Decrease the temperature of its solution. Tags: Carboxylic Acids | Acid Derivatives |

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Q: Esterification occurs when a carboxylic acid reacts with: A a ketone. B an alcohol. C another carboxylic acid. D an amine. Tags: Carboxylic Acids | Alcohols | Acid Derivatives |

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Q: Which of the following is the correct structure of an organic acid anhydride? A two acyl groups bonded to one oxygen atom B two acyl groups bonded to one carbon atom C an acyl group bound to an amide D an acyl group bound to an acid Tags: Acid Derivatives |

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Q: Which amino acid is able to form the linkage shown in Figure A, after undergoing a redox reaction? A Methionine B Serine C Threonine D Cysteine Tags: Acid Derivatives |

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