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MCAT Question of the Day
Q:
A contentious issue in stem cell biology is whether mesenchymal stem cells differentiate into cartilage, bone, and fat tissue
in vivo
or if those effects are only seen
in vitro
. How might researchers design an experiment to confirm
in vivo
differentiation?
A
Inject a mouse with labeled mesenchymal stem cells that have been cultured
in vitro
and track the label at common sites of differentiation.
B
Treat mice with a drug that targets mesenchymal stem cells and measure the production of bone, cartilage, and fat tissues.
C
Mutate a line of mice to produce a label on their mesenchymal stem cells, and track the activity of the cells at common sites of differentiation.
D
Track the population of mesenchymal stem cells in mice as they age and begin to produce less bone, cartilage, and fat tissue.
Miscellaneous Biology
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